RT-qPCR-based microneutralization assay for human cytomegalovirus using fibroblasts and epithelial cells
نویسندگان
چکیده
منابع مشابه
Neutralization of Human Cytomegalovirus Entry into Fibroblasts and Epithelial Cells
Human cytomegalovirus (HCMV) is a leading cause of permanent birth defects, highlighting the need to develop an HCMV vaccine candidate. However, HCMV vaccine development is complicated by the varying capacity of neutralizing antibodies (NAb) to interfere in vitro with the HCMV entry routes mediating infection of fibroblast (FB) and epithelial cells (EC). While HCMV infection of FB and EC requir...
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ژورنال
عنوان ژورنال: Vaccine
سال: 2015
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2015.10.110